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  Indian J Med Microbiol
 

Figure 1: Flowchart shows the procedure of the study. All participants included in the study (536 Han and 588 Li) carried a mutated α-globin and/ or β-globin gene diagnosed by PCR test in pre-pregnancy. These participants underwent prenatal diagnosis by amniocentesis during pregnancy because they may have next generations with high risks of medium or severe thalassemia. Amniotic fluid DNA was diagnosed by GAP-PCR and PCR-RDB. Our study performed a statistical analysis and comparison according to diverse fetal thalassemia genotypes and mutated alleles in Han and Li participants.

Figure 1: Flowchart shows the procedure of the study. All participants included in the study (536 Han and 588 Li) carried a mutated <i>α-globin</i> and/ or <i>β-globin</i> gene diagnosed by PCR test in pre-pregnancy. These participants underwent prenatal diagnosis by amniocentesis during pregnancy because they may have next generations with high risks of medium or severe thalassemia. Amniotic fluid DNA was diagnosed by GAP-PCR and PCR-RDB. Our study performed a statistical analysis and comparison according to diverse fetal thalassemia genotypes and mutated alleles in Han and Li participants.