Figure 4: Effects of nacre extract on scopolamine-induced memory impairment of rats in Barnes maze test. (A) Latency time in training session. Rats were injected intraperitoneally with PBS and scopolamine (closed circle, dotted line) or nacre extract and scopolamine (open circle, dashed line). In control rats, PBS only was injected (triangle, solid line). (B) Searching time in a probe test. Data were expressed as mean ± SD. Different letters between groups indicate statistically significant difference (P < 0.05).