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Figure 3: Nissl stained sections of mice cortex. The stained sections of AlCl3•6H2O treated cortex showed marked neurotoxicity in comparison to respective negative controls. Reduced cell count and structural deformity is also visible in the sections treated with AlCl3•6H2O while restoration of cell count is evident after the administration of S. aromaticum. Where (a) Negative Control, (b) AlCl3•6H2O (300 mg/kg)- treated, (c) Self-recovery, (d) AlCl3•6H2O + S. aromaticum (500 mg/kg)- treated, (e) S. aromaticum-treated (500 mg/kg). Original magnification, I; 4 ×, II; 10 ×, III; 40 ×. (IV) Histograms representing cell count/10 000 μm2 (at 10 × magnification) in cortex in all experimental groups. |
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