| CASE REPORT |
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| Year : 2022 | Volume
: 15
| Issue : 4 | Page : 183-185 |
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Membranous nephropathy associated with tuberculosis-a case report
Madhumita Pal1, Moumita Sengupta1, Keya Basu1, Arpita Roychowdhury2
1 Department of Pathology, IPGME&R and SSKM Hospital, Kolkata, India
2 Department of Nephrology, IPGME&R and SSKM Hospital, Kolkata, India
Correspondence Address:
Arpita Roychowdhury
Department of Nephrology, IPGME&R and SSKM Hospital, Kolkata
India
 Source of Support: The authors received no extramural funding for the study, Conflict of Interest: None
DOI: 10.4103/1995-7645.340571
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Rationale: Genitourinary tuberculosis can develop during the disease course of disseminated disease and the distinctive histological finding is epithelioid granuloma with or without caseation and accompanied Langhans-type giant cells. Barely, the lesion is only restricted to kidney involving both glomerular and extraglomerular compartment. Association with immune complex-mediated glomerulonephritis has been sparsely reported in the literature.
Patient concern: A 42-year-old non-diabetic, non-hypertensive male presented with generalized body swelling and frothing of urine for 3 months.
Diagnosis: Membranous nephropathy with tuberculous interstitial nephritis.
Intervention: Anti-tuberculous therapy for extrapulmonary tuberculosis was administered along with low dose corticosteroid.
Outcomes: Reduction of proteinuria was achieved at one month follow-up visit.
Lessons: Tuberculosis should be considered as a potentially treatable cause of secondary membranous nephropathy as pharmacotherapy greatly helps improve the outcome. |
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