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Year : 2022  |  Volume : 15  |  Issue : 4  |  Page : 183-185

Membranous nephropathy associated with tuberculosis-a case report

1 Department of Pathology, IPGME&R and SSKM Hospital, Kolkata, India
2 Department of Nephrology, IPGME&R and SSKM Hospital, Kolkata, India

Correspondence Address:
Arpita Roychowdhury
Department of Nephrology, IPGME&R and SSKM Hospital, Kolkata
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Source of Support: The authors received no extramural funding for the study, Conflict of Interest: None

DOI: 10.4103/1995-7645.340571

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Rationale: Genitourinary tuberculosis can develop during the disease course of disseminated disease and the distinctive histological finding is epithelioid granuloma with or without caseation and accompanied Langhans-type giant cells. Barely, the lesion is only restricted to kidney involving both glomerular and extraglomerular compartment. Association with immune complex-mediated glomerulonephritis has been sparsely reported in the literature. Patient concern: A 42-year-old non-diabetic, non-hypertensive male presented with generalized body swelling and frothing of urine for 3 months. Diagnosis: Membranous nephropathy with tuberculous interstitial nephritis. Intervention: Anti-tuberculous therapy for extrapulmonary tuberculosis was administered along with low dose corticosteroid. Outcomes: Reduction of proteinuria was achieved at one month follow-up visit. Lessons: Tuberculosis should be considered as a potentially treatable cause of secondary membranous nephropathy as pharmacotherapy greatly helps improve the outcome.

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