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Year : 2021  |  Volume : 14  |  Issue : 5  |  Page : 231-233

Extensively drug-resistant Salmonella typhi causing rib osteomyelitis: A case report

1 Section of Cardiothoracic Surgery, Department of Surgery, Aga Khan University Hospital, Pakistan
2 Medical College, Aga Khan University, Pakistan

Correspondence Address:
Humza Thobani
Medical College, Aga Khan University
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1995-7645.315892

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Rationale: Salmonella (S.) typhi is a rare cause of osteomyelitis in immunocompetent adults. Extensive drug resistance (XDR) may lead to more complicated cases of S. typhi osteomyelitis. Patient concern: A 55-year-old female presented with a persistent low-grade fever and a swelling on her lower left chest with a sinus discharging purulent fluid for the past 8 months. Her symptoms had been unresponsive to previous anti-microbial therapy. Diagnosis: Rib osteomyelitis caused by XDR S. typhi. Interventions: Surgical wound debridement, left 7th-9th rib resection and intravenous IV meropenem were done. Outcome: Fever resolved and left-sided swelling resected without recurrence. Lessons: The prevalence of XDR S. typhi is growing in South Asia and should be considered as the differential diagnosis of chronic osteomyelitis.

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