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  Indian J Med Microbiol
 

Figure 3: Kaplan-Meier curves. The percentage of women given intermittent preventative treatment in pregnancy with sulfadoxine-pyrimethamine (IPTp-SP) and who remain infection free over the second and third trimesters of pregnancy when given (i) the currently recommended three-dose regimen ([9]; top panels) or (ii) 4, 6,8 weekly regimens (middle panels) or (iii) the previously recommended two-dose regimen ([15]; bottom panels). The panel columns show how the effectiveness of IPTp regimens change as the entomological inoculation rate (EIR) increases from 1 (left panels), to 10 (center panels), to 100 (right panels). The black arrows indicate the timing of recommended IPTp-SP doses in the second trimester (orange-shaded region) and third trimester (blue-shaded region). The solid black line on top panels represents full adherence while the coloured lines on that panel represent the effect of missed doses. Each colour line represents a specific scenario in middle and bottom panels (see Figure 2 and main text for more details).

Figure 3: Kaplan-Meier curves. The percentage of women given intermittent preventative treatment in pregnancy with sulfadoxine-pyrimethamine (IPTp-SP) and who remain infection free over the second and third trimesters of pregnancy when given (i) the currently recommended three-dose regimen (<sup>[9]</sup>; top panels) or (ii) 4, 6,8 weekly regimens (middle panels) or (iii) the previously recommended two-dose regimen (<sup>[15]</sup>; bottom panels). The panel columns show how the effectiveness of IPTp regimens change as the entomological inoculation rate (EIR) increases from 1 (left panels), to 10 (center panels), to 100 (right panels). The black arrows indicate the timing of recommended IPTp-SP doses in the second trimester (orange-shaded region) and third trimester (blue-shaded region). The solid black line on top panels represents full adherence while the coloured lines on that panel represent the effect of missed doses. Each colour line represents a specific scenario in middle and bottom panels (see Figure 2 and main text for more details).