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  Indian J Med Microbiol
 

Figure 4: Effects of PA and RN extracts on mRNA levels of melanogenic enzymes in the reconstitutive skin model. (A) MITF, (B) TYR, (C) TYRP1, and (D) DCT were examined by qPCR, using GAPDH as an internal control. *P<0.05, **P<0.01, ***P<0.001 compared with α-MSH treated cells. KA 125: kojic acid at 125 μg/mL.

Figure 4: Effects of PA and RN extracts on mRNA levels of melanogenic enzymes in the reconstitutive skin model.
(A) <i>MITF</i>, (B) <i>TYR</i>, (C) <i>TYRP1</i>, and (D) <i>DCT</i> were examined by qPCR, using GAPDH as an internal control. *<i>P</i><0.05, **<i>P</i><0.01, ***<i>P</i><0.001 compared with α-MSH treated cells. KA 125: kojic acid at 125 μg/mL.