Impact Factor 2018: 1.772 (@Clarivate Analytics)
5-Year Impact Factor: 1.772 (@Clarivate Analytics)
  • Users Online: 1687
  • Print this page
  • Email this page
ORIGINAL ARTICLE
Year : 2019  |  Volume : 12  |  Issue : 11  |  Page : 520-527

Nanoemulsified Mentha piperita and Eucalyptus globulus oils exhibit enhanced repellent activities against Anopheles stephensi


1 Health Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran
2 Iranian Research Institute of plant protection, Tehran, Iran
3 Faculty of Agriculture, Department of Plant Protection, University of Tabriz, Tabriz, Iran

Correspondence Address:
Mehdi Khoobdel
Health Research Center, Baqiyatallah University of Medical sciences, Tehran
Iran
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1995-7645.271292

Get Permissions

Objective: To formulate nanoemulsion from essential oils of Mentha (M.) piperita L. and Eucalyptus (E.) globulus L. and to compare their repellant activity with normal essential oils and N,N-diethyl-m toluamide (DEET) as a standard chemical compound. Methods: In this study, protection time of essential oils and DEET was evaluated on four human subjects using test cage, and their values were determined against Anopheles stephensi. Furthermore, ED50 values for the above essential oils were determined using the ASTM E951- 94 method. The compositions of essential oils were determined using GC-MS, and droplet size and zeta potential of the nanoemulsion were measured with dynamic light scattering. Results: The results (expressed as mean±SD) showed that protection time of M. piperita 50%, M. piperita Nano 50%, E. globulus 50%, E. globulus Nano 50%, and DEET 25% was (2.89±0.45) h, (4.17±0.28) h, (0.96±0.27) h, (5.51±0.02) h, and (6.10±0.47) h, respectively. ED50 values were 29.10 (95% CI: 23.36-36.06) μg/cm2 for Mentha, 19.39 (15.35-23.99) μg/cm2 for Mentha Nano, 36.10 (28.70-48.01) μg/cm2 for Eucalyptus, 18.50 (14.65-23.23) μg/cm2 for Eucalyptus Nano, and 3.62 (2.68-4.55) μg/cm2 for DEET, respectively. E. globulus Nano and M. piperita Nano provided significantly longer protection than normal essential oils E. globulus and M. piperita (P<0.01). Conclusions: The preparation of nanoemulsion from the essential oils of M. piperita and E. globulus, significantly increases the protection time and reduces ED50 values of these essential oils, hence, M. piperita Nano and E. globulus Nano can be good alternatives to DEET and other chemical compounds.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed102    
    Printed0    
    Emailed0    
    PDF Downloaded51    
    Comments [Add]    

Recommend this journal