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REVIEW ARTICLE
Year : 2018  |  Volume : 11  |  Issue : 1  |  Page : 15-23

Scenario of dengue infection & its control in Pakistan: An up—date and way forward


1 Department of Biological Sciences Forman Christian College (A Chartered University), Ferozpur Road, 54600, Lahore, Pakistan
2 Department of Bioinformatics and Biotechnology, Government College University Faisalabad, Pakistan
3 Department of Biotechnology, Quad-e Azam University Islamabad, Pakistan

Correspondence Address:
Usman Ali Ashfaq
Department of Bioinformatics and Biotechnology, Government College University Faisalabad
Pakistan
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1995-7645.223529

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Dengue fever is one of the major health problems in tropical and subtropical areas throughout the world. The causative agent of dengue fever is the dengue virus which is an enveloped single stranded RNA virus belongs to the family Flaviviridae and has five distinct serotypes (DENV-1, DENV-2, DENV-3, DENV-4 and DENV-5). Dengue virus is transmitted to human via bite of Aedes aegypti and Aedes albopictus mosquitoes. The clinical symptoms of dengue fever ranging from mild to severe fonn as dengue hemorrhagic fever and dengue shock syndrome. Pakistan is dengue endemic since 1994 but from 2006, Pakistan faced the worst condition regarding dengue in which thousands of people affected by the disease and hundreds of people lost their lives. DENV-2, DENV-3 and DENV-1 are the prevalent serotypes in Pakistan. Common diagnostic techniques are being used in Pakistan such as enzyme-linked immunosorbent assay, polymerase chain reaction and rapid diagnostic tests, while differential diagnosis, limitations of diagnostic methods and poor health care system are the real challenges in dengue diagnosis. Favorable climatic conditions, unplanned urbanization, travelling etc., are major factors responsible for dengue epidemics in Pakistan. This presentation provides update about dengue circumstances in Pakistan and also describes the way how to improve dengue situation in Pakistan.


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